The Chu Lab
Life depends on transmitting genetic information encoded on DNA reliably from cell to cell and generation to generation.
Our diverse team of researchers investigates molecular mechanisms that package and transmit DNA during sperm formation that are needed for fertility and development.
Because these processes are critical for fertility, they are highly conserved across species. We therefore use the tiny roundworm C. elegans as a model organism to study sperm formation. This allows us to use a broad range of approaches in biochemistry, cell biology, biophysics, bioinformatics, molecular biology, and genetics that are difficult to conduct in humans.
Our work has been published in Nature and PLoS Genetics and is funded by the National Science Foundation and National Institutes of Health. We invite you to explore our work!
Click to read more: Sperm DNA (top, red) has the HTAS-1 H2A variant but oocyte DNA (bottom, blue) does not.
Outside the lab
We share our science and stories with our communities to inspire everyone that science is amazing and enriches our lives every day. We believe that people of all ages and from all walks of life can be a scientists.
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